Case Control Study to Identify Modifiable Risk Factors for Colorectal and Breast Cancer in Nigeria

Status: Recruiting
Location: See location...
Intervention Type: Behavioral, Device
Study Type: Observational
SUMMARY

This project is a case-control study which seeks to identify modifiable risk factors for breast and colorectal cancer in Nigeria. Both cases and controls will be required to complete a risk factor questionnaire which contains information about their diet, physical activity, past medical history and life style factors. They will also be required to provide information on their body composition through the use of a bioimpedance machine which measures the body mass index, fat and total body water percentage. Based on the existing ARGO platform where a current colorectal cancer study is going on, approximately 400 patients with a prior diagnosis or a new diagnosis will be recruited into this study. Comparatively, we will select our 400 controls from two groups of participants who are free of cancer and gastrointestinal diseases.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: t
View:

• Case Group - Patients must have histologically confirmed diagnosis of colorectal or breast cancer.

• Control Group - Patients must not have a diagnosis of cancer.

Locations
Other Locations
Nigeria
Obafemi Awolowo University Teaching Hospitals
RECRUITING
Ile-ife
Time Frame
Start Date: 2021-04-12
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 800
Treatments
Colorectal Cancer (Cases)
Based on the existing ARGO (African Colorectal Cancer Group) platform where a current colorectal cancer study is going on, 400 patients with a prior diagnosis and a new diagnosis will be recruited into this study.
Controls
We will select our 400 controls from two groups of participants who are free of cancer and gastrointestinal diseases. First, we will leverage community mobilization groups to identify and recruit a target group of 200 community-based population controls. Second, we will identify and recruit the remaining 200 controls from those seeking care in the Outpatient Health Center at OAU, which sees \~50-60 patients per day as part of routine care.
Related Therapeutic Areas
Sponsors
Collaborators: Memorial Sloan Kettering Cancer Center, Federal Medical Centre, Owo, Lagos State University, University of Maiduguri Teaching Hospital, University of Ilorin Teaching Hospital, National Hospital, Abuja
Leads: Obafemi Awolowo University Teaching Hospital

This content was sourced from clinicaltrials.gov